CORDIS Servizio Comunitario di Informazione in materia di Ricerca e Sviluppo

Project objective

The strategic objective of the proposed Network of Excellence, applying for EC support for 4 years, is the integration of 31 research teams (including a SME) working on genetics, functional genomics and molecular mechanisms of hypertension and hypertension-related cardiac and vascular damage and 1 SME experienced in EC project management, in 11 EC countries, 1 Associated State (Switzerland), and two countries having S&T cooperation agreements with EU (Russian Federation and China) by integrating complementary but still fragmented experiences in studying the physiological mechanisms of blood pressure control and hypertension development, in phenotyping initiation and progression of organ damage and in exploring genetics, genomics and proteomics of hypertension-related disease.

In more detail, a first group of joint research activities (A) will be centred on mechanomics of hypertension, that is on genetics, genomics and proteomics of the major mechanisms responsible for blood pressure regulation and implicated in development of hypertension. A second group of joint research activities (B) will be more specifically centred on mechanomics of hypertension-related cardiovascular damage, that is on genetics, genomics and proteomics of the major complications of hypertension. In each of the coordinated packages, the first objective will be the collection of the subject samples (populations, cohorts, families).

The European Union On-LineAcknowledgement of support from the Sixth Framework Programme, Thematic priority1: Life sciences, genomics and biotechnology for health contract InGenious HyperCare (LSHM-CT-2006-037093)